Origin of the Malaria Parasite

  • Human chromosomesOriginated less than 120,000 ya

  • Resistance alleles appeared 3,000-12,000 ya

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Slide 35 of 109


Depending upon which study one examines the alleles that confer malarial resistance arose either 120,0001 or 3,000-12,0002 year ago.


References Top of page

  1. Mu, J., J. Duan, K. D. Makova, D. A. Joy, C. Q. Huynh, O. H. Branch, W. Li and X. Su. 2002. Chromosome-wide SNPs reveal an ancient origin for Plasmodium falciparum. Nature 418: 323–324.

  2. Tishkoff, S.A., et al. 2001. Haplotype Diversity and Linkage Disequilibrium at Human G6PD: Recent Origin of Alleles That Confer Malarial Resistance. Science 293: 455-462.


Last Modified June 21, 2006