Chromosome 21 - Human-Chimp Comparison

  • Chromosome 21 fully sequenced and annotated

  • Two clusters with significant differences

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Slide 72 of 109


A first-generation human-chimpanzee comparative genome map was made by scientists who paired alignment of 77,461 chimpanzee bacterial artificial chromosome end sequences with the recently published human genome sequence.1 They detected two clusters on human chromosome 21 that suggest large, nonrandom regions of difference from the chimpanzee genome.


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  1. Fujiyama, A. et al. 2002. Construction and Analysis of a Human-Chimpanzee Comparative Clone Map. Science 295: 131-134.


Last Modified June 21, 2006