Polymorphic Alu A type of chromosomal abnormality in which a DNA sequence is inserted into a gene, disrupting the normal structure and function of that gene.Insertions

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The Alu family of retroposons is present at an extremely large copy number within the Threadlike "packages" of genes and other DNA in the nucleus of a cell. Different kinds of organisms have different numbers of chromosomes. Humans have 23 pairs of chromosomes, 46 in all: 44 autosomes and two sex chromosomes. Each parent contributes one chromosome to each pair, so children get half of their chromosomes from their mothers and half from their fathers.chromosomes of the human All the DNA contained in an organism or a cell, which includes both the chromosomes within the nucleus and the DNA in mitochondria.genome (500,000 copies/ All the DNA contained in an organism or a cell, which includes both the chromosomes within the nucleus and the DNA in mitochondria.genome equivalent), representing approximately 10% of its mass. The majority of these elements are thought to be transcriptionally inactive Sequence of DNA that are very similar to normal genes but that has been altered so they are not expressed.pseudogenes. The distribution of the polymorphic Alu Chromosomal abnormalities in which a DNA sequences are inserted into genes, disrupting the normal structure and function of those genes.insertions is variable within population groups from different geographic origins, and is not random along individual human Threadlike "packages" of genes and other DNA in the nucleus of a cell. Different kinds of organisms have different numbers of chromosomes. Humans have 23 pairs of chromosomes, 46 in all: 44 autosomes and two sex chromosomes. Each parent contributes one chromosome to each pair, so children get half of their chromosomes from their mothers and half from their fathers.chromosomes.

A study examined 5 polymorphic Alu Chromosomal abnormalities in which a DNA sequences are inserted into genes, disrupting the normal structure and function of those genes.insertions in 895 unrelated individuals from 24 Native American populations compared to a worldwide population survey.¹ The results showed a close similarity between the Chinese and Native Americans, demonstrating a recent The functional and physical unit of heredity passed from parent to offspring. Genes are pieces of DNA, and most genes contain the information for making a specific protein.gene flow from Asia.

References

1. Novick GE, Novick CC, Yunis J, Yunis E, Antunez de Mayolo P, Scheer WD, Deininger PL, Stoneking M, York DS, Batzer MA, Herrera RJ. 1998. Polymorphic Alu Chromosomal abnormalities in which a DNA sequences are inserted into genes, disrupting the normal structure and function of those genes.insertions and the Asian origin of Native American populations. Hum. Biol. 70:23-39.